1. DIP — Database of Interacting Proteins
Bio: DIP is a public database that catalogs experimentally determined physical interactions between proteins. It combines curated data from scientific studies into a consistent set of protein–protein interactions, helping researchers explore how proteins physically connect in cells.
Link: dip.doe
2. BioGRID — Biological General Repository for Interaction Datasets
Bio: BioGRID is a large, open-access repository of biological interactions, including protein–protein, genetic, and chemical interactions compiled from published studies. It covers data from many organisms and is widely used for interactome research.
Link: Thebiogrid
3. MINT — Molecular INTeraction Database
Bio: MINT is a curated database focused on experimentally supported molecular interactions, particularly physical contacts between proteins reported in peer-reviewed journals. It follows community standards (PSI-MI) and is part of efforts to share interaction data across resources.
Link: Mintbio
4. IntAct — Molecular Interaction Database
Bio: IntAct is an open-source protein interaction database maintained by the European Bioinformatics Institute (EBI). It provides detailed, experimentally verified molecular interaction data with tools for visualization, search, and download.
Link: IntAct